A Center of Excellence for Biomedical Research and Training in Africa


Compared to adults’ children have poor HIV testing, treatment and programmatic outcomes. To achieve the UNAIDS 90-90-90 targets, there is now an urgent need to improve HIV testing and engagement with HIV treatment and care services among children and adolescents - a group that is difficult to reach and has lower treatment success.


Impaired linear growth (stunting), is one of the most common manifestations of vertically-acquired HIV which can adversely impact bone and muscle development and function, particularly during adolescence - a critical period of somatic growth. We hypothesize that the accrual of bone mass in children with HIV during growth may be reduced, which will put them at increased risk of adverse musculoskeletal outcomes e.g. fracture risk earlier in life compared to uninfected peers.


FIEBRE is a multi-disciplinary project, led by the London School of Hygiene & Tropical Medicine, that is investigating the leading causes of fever in children and adults attending primary care health services and those admitted to district hospitals in Laos, Malawi, Mozambique, Myanmar and Zimbabwe. This is the largest study of its kind, aiming to tackle antimicrobial resistance and develop a ‘blueprint’ for treatment.


CHIEDZA is a cluster randomised trial which is Community based interventions to improve the HIV outcomes in young people. Adolescents and Young People (AYP) fare disproportionately poorly across the HIV care continuum compared to other age-groups: the prevalence of undiagnosed HIV is substantially higher, and coverage of and adherence to ART is lower, resulting overall in worse virological outcomes.


Chiedza’s song tells the true story of a young woman growing up with HIV in Harare. Its message is positive. Chiedza overcomes serious illness and family rejection to get to university and find love. The film was designed with the participation of young people living with HIV in Harare, to challenge the stereo-typed images of HIV still prevalent. It is shot entirely through Chiedza’s eyes so that the audience sees what she sees and hears what she thinks.